Modifiable factors and determinants associated with poor lipid control in individuals with high cardiovascular risk

SEX

Male

47 (64.4%)

180 (67.9%)

0.568 b

OR=0.579

Female

26 (35.6%)

85 (32.1%)

AGE (years)

0.056 a

D Cohen=0.210

Mean ± S.D

66.5± 10.8

68.9 ±11.1

CIVIL STATUS

Single

56 (76.7%)

227 (85.7%)

0.149 b

OR=0.570

Married

16 (21.9%)

37 (14%)

Unknown

1 (1.4%)

1 (0.38%)

SMOKING

Current smoker

7 (9.6%)

28 (10.6%)

0.808 b

C= 0.036

Former smoker

13 (17.8%)

55 (20.8%)

Non Smoker

53 (72.6%)

182 (68.7%)

ALCOHOL CONSUMPTION

Yes

24 (32.9%)

72 (27.2%)

0.338 b

C=0.052

No

49 (67.1%)

193 (72.8%)

COMORBIDITIES

HTN

51 (15.1%)

233 (68.9%)

<0.001 b

OR=1.34

DM

28 (38.3%)

114 (43%)

0.475 b

OR=0.193

CKD

3 (4.1%)

17 (6.4%)

0.460 b

OR=1.60

Past history of dyslipidemia

15 (20.5%)

74 (27.9%)

0.205 b

OR=1.50

Past history of ACS

35 (10.4%)

135 (39.9%)

0.650 b

OR=1.13

Past history of CVA

0

15 (5.7%)

0.038 b

0R=9.10

MEDICATION

Moderate-intensity statin monotherapy

8 (10.9%)

53 (20%)

0.023a

C=0.148

High-intensity statin monotherapy

65 (89.1%)

201 (75.8%)

High-intensity statin + Ezetimibe combination therapy

0 (0.0%)

10 (3.8%)

CHANGES IN TREATMENT

Substitution of drug

4 (5.5%)

24 (9.1%)

0.397a

C=0.135

Increase in dose

4 (5.5%)

34 (12.8%)

Addition of a new drug

1 (1.4%)

6 (2.3%)

Decrease in dose

19 (26%)

50 (18.9%)

Removing of a drug

2 (2.7%)

9 (3.4%)

No changes

43 (58.9%)

142 (53.6%)

Yes n (%)

No n (%)

High intensity statin

137 (44.3)

129 (41.7)

3.03

0.220

0.095

Moderate intensity Statin

24 (7.8)

26 (8.4)

Combined therapy**

6 (1.9)

4 (1.3)

LDL-c goal< 70mg/dL

Not achieved

Achieved

High intensity statin/Combined therapy

166 (53.7)

86 (27.8)

7.41

0.025

0.153

Moderate intensity Statin

26 (8.4)

22 (7.1)

Combined therapy**

9 (2.9)

0

Survival status

Deceased

Alive

High intensity statin/Combined therapy

4 (1.3)

262 (84.8)

3.15

0.207

0.096

Moderate intensity Statin

3 (0.9)

57 (18.4)

Combined therapy**

0

10 (3.2)

LDL-c goal (<70 mg/dL)

Achieved

44 (32%)

53 (32%)

0.66

Not achieved

78 (57%)

105 (63%)

ACS* recurrence

Yes

78 (57%)

74 (44%)

0.024

No

58 (43%)

93 (56%)

Discharge status

Deceased

4 (3%)

2 (1%)

0.279

Alive

132 (97%)

165 (99%)