MPOX (Previamente Viruela del Simio) y Coinfecciones con VIH en República Dominicana: Una serie de casos
Despite being endemic in regions of Central Africa, the Mpox virus (previously Monkeypox virus) has not been extensively characterized in non-endemic countries such as those in the Latin American region. This is further accentuated by co-infections with HIV, which are scarcely represented in current scientific literature. Here, we present five clinical cases of coinfections of Mpox and HIV, their clinical characteristics, and biological infection markers (CD4:CD8).
Results: The occurrence of clinical manifestations and their complications depends on the pro-inflammatory reactions induced by the host, antiretroviral treatment, and early symptomatic management, which could modify the complications and hospitalizations observed in other non-endemic Mpox environments during the 2022-2023 outbreak. Pro-inflammatory stimulation provides some clues as to what type of markers to observe during future Mpox outbreaks and their clinical prognostic utility.
Keywords:
Mpox; monkeypox virus; HIV; Dominican Republic
