Cambios en el perfil oncológico en nefrología desde 2015-2023, hgps, santo domingo, república dominicanaIntroduction: The oncologic profile of nephrology patients in the Dominican Republic (DR) has not been shared with the scientific community.
Objective: Determine changes in the oncologic profile in nephrology, from 2015-2023, HGPS, Santo Domingo, DR.
Materials and methods: Quantitative observational descriptive retrospective cohort study. 103 patients were evaluated with histopathological analysis of their renal neoplasia in a tertiary level hospital in the DR from 2015 to 2023. The following variables were evaluated: sex, age at diagnosis, presence of metastases, clinical presentation, and risk factors. Data analysis was descriptive and inferential.
Results: Mean age of 55.28 ± 15.38 years and male sex in 51.46%. Benign and malignant renal neoplasms predominated significantly more in women (82.35%) and men (57.14%), respectively. The most common type and subtype of primary neoplasia was renal cell carcinoma (RCC) (74.26%) and clear cell carcinoma (CCC) (37.62%), respectively. The most common symptomatic clinical presentation was pain in the abdomen/flank (30.10%). The most frequent risk factor was tobacco smoking (11.65%). A decrease in the incidence of renal neoplasms was seen from 2019-2022. The most frequent neoplasia in the years 2015-2019 was CCC (57.14%, 46.67%, 40.00% and 50.00%, respectively). In 2020, the most common was unclassified carcinoma (36.36%) and, in 2021, papillary carcinoma (33.33%). In 2022 and 2023, there was no predominant neoplasia.
Conclusion: This study provides local data that allows for informed health decisions to be made that are more tailored to the needs of the population.
Keywords:
Dominican Republic; nephrology; oncology; pathology; renal neoplasms
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